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Chapter 15
— Taishi Ci Fights With The Young Overlord; Sun Ce Cuts Short The White Tiger King.
Hua Tuo's first appearance - physician who treats Zhou Tai's many wounds. Will reappear later treating Guan Yu and Cao Cao.
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Chapter 29
— The Little Chief Of The South Slays Yu Ji; The Green Eyed Boy Lays Hold On The South Land.
Hua Tuo; sent for by the dying Sun Ce; pronounces him untreatable due to the poison-arrow wound's spread.
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Chapter 75
— Guan Yu Has A Scraped-Bone Surgery; Lu Meng Crosses The River In White Robe.
Hua Tuo; arrives at Guan Yu's camp from across the river and operates on the poisoned arm - scrapes the bone clean with no anaesthetic; admires Guan Yu's iron will. The novel's most famous surgery scene.
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Chapter 78
— Treating A Headache, A Famous Physician Dies; Giving The Last Words, The Crafty Hero Departs.
Hua Tuo; summoned to treat Cao Cao's head-pain. Proposes opening the skull with an axe to remove the source - Cao Cao thinks he means to murder him in revenge for Guan Yu; throws Hua Tuo in prison where he dies of starvation. With him dies his Book of the Black Bag - the jailer's wife burns the manuscript while it is being copied by a grateful jailer. Chinese medicine's great loss.